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Greatest MLB Bets for Wednesday Might twenty first: Prime Picks & Predictions


Might 20, 2025; Milwaukee, Wisconsin, USA; Milwaukee Brewers outfielder Sal Frelick (10) rounds the bases after hitting a house run towards the Baltimore Orioles within the fourth inning at American Household Area. Obligatory Credit score: Michael McLoone-Imagn Pictures

Hump Day may as properly be referred to as “Guess on Baseball” Day.

With one other 15 video games on the schedule, there are innumerable markets to guess on midweek.

Perhaps my checklist of Greatest MLB Bets for Wednesday will help you out.

I like to recommend line looking for higher costs, however for the aim of this checklist, odds are through FanDuel until in any other case said.

Chicago Cubs (-1.5) vs. Miami Marlins (+112), o/u 8.5

The Chicago Cubs are the hottest-hitting staff in baseball proper now, batting .326 during the last week. Miami will ship Max Meyer (3-4, 4.47 ERA, 1.33 WHIP) to the mound. He’s allowed 5 runs in three of his final 4 begins.

Cubs starter Cade Horton is healthier than his 6.00 ERA suggests, however it could not matter if the Marlins handle a number of runs. If Chicago doesn’t destroy Meyer, they’ll possible tough up Miami’s struggling bullpen.

Decide: Cubs -1.5 at +126

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Baltimore Orioles (+1.5) vs. Milwaukee Brewers (-126), o/u 8.5

Baltimore has misplaced eight straight, together with two to the Brewers. The Orioles are hitting simply .242 during the last week, and dealing with Brewers starter Chad Patrick (2-4, 3.35 ERA, 1.28 WHIP) isn’t going to make issues simpler.

The Brewers, hitting .230 during the last week, received’t have it straightforward towards Tomoyuki Sugano (3.08 ERA, 1.03 WHIP) both. As unhealthy because the Orioles have been, I’d lean towards Milwaukee on the moneyline when you’re selecting a winner.

However the UNDER is a a lot stronger play. Add the Brewers moneyline (-126) in a same-game parlay, and also you’ll get +212 odds.

Decide: UNDER 8.5

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